But then you can get into the problem of estrogen dominance which can stimulate the growth of breast cancer. As far as I know, only the herbs bloodroot and mandrake have been shown to both block progesterone and suppress estrogen receptor positive breast cancer.
Since progesterone is produced in large amounts by the ovaries, sometimes a complete hysterectomy or ovarianectomy can give some relief, but the adrenals can still produce progesterone. And we definitely need it, but not in large enough amounts to inhibit the chloride channel function. During pregnancy progesterone is produced by the placenta, which is why myotonia often improves for women who were miserable during their pregnancy shortly after they give birth.